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Hill Lab

Recent Highlights

Publication!

2-14-2025
Daniel's paper titled, "Dietary Branched‐Chain Amino Acids Modify Postinfarct Cardiac Remodeling and Function in the Murine Heart" was published in Journal of the American Heart Association. This study provides proof‐of‐principle using a preclinical mouse model that dietary constituents can have marked effects on cardiac remodeling after myocardial infarction.

Successful Defense!

2-12-2025
Congratulations to Daniel Nguyen, who successfully defended his dissertion today! He will be returning to medical school to complete the rest of his MD/PhD training. The man is a beast (in the best possible way!) and he will be a stellar physician-scientist!

Publication!

12-12-2024
Kara's paper titled, "Myocardial Hyperemia via Cardiomyocyte Catabolism of β-Hydroxybutyrate" was published in Arteriosclerosis, Thrombosis, and Vascular Biology. This study shows that the circulating ketone, β-Hydroxybutyrate, increases myocardial perfusion and that its hyperemic effects are dependent on cardiomyocyte catabolism. The article was chosen for the cover image of the journal, with a local artist, Mr. Trevor Inkwell, kindly providing his artwork titled "Main Squeeze."

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Publication!

01-2025
Tyler Jobe's paper titled, "Phase partitioning of the neutrophil oxidative burst is coordinated by accessory pathways of glucose metabolism and mitochondrial activity" was published in The Journal of Biological Chemistry. This study shows how neutrophils leverage multiple metabolic pathways to titrate the oxidative burst.  This study is an example of the highly collaborative environment in the Center for Cardiometabolic Science.  Tyler is a student of Dr. Marcin Wysoczynski, with whom we have collaborative projects.  

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